Peer-reviewed publications
Human genetic variability of immune system contribution
Bruna Kulmann-Leal, Joel Henrique Ellwanger, Jacqueline María Valverde-Villegas, Daniel Simon, et al. TLR9 2848 G/A Gene Polymorphism in HCV+, HIV+, and HCV+/HIV+ Individuals. Genet Test Mol Biomarkers, 2022. https://pubmed.ncbi.nlm.nih.gov/35575727/
​
Joel Henrique Ellwanger, Bruna Kulmann Leal, Jacqueline María Valverde-Villegas, Daniel Simon, Camila Guerra Marangon, Vanessa Suñé Mattevi, Rosmeri Kuhmmer Lazzaretti, Eduardo Sprinz, Regina Kuhmmer, José Artur Bogo Chies. CCR5Δ32 in HCV infection, HCV/HIV co-infection, and HCV-related diseases. Infect Genet Evol. 2018. https://pubmed.ncbi.nlm.nih.gov/29408489/
​
Joel Henrique Ellwanger, Valéria de Lima Kaminski, Jacqueline María Valverde-Villegas, Daniel Simon, Vagner Ricardo Lunge, José Artur Bogo Chies. Immunogenetic studies of the hepatitis C virus infection in an era of pan-genotype antiviral therapies-Effective treatment is coming. Infect Genet Evol. 2017. https://pubmed.ncbi.nlm.nih.gov/28811194/
​
Jacqueline M Valverde-Villegas, Rúbia M de Medeiros, Karine P de Andrade, Vanessa C Jacovas, Breno R Dos Santos, Daniel Simon, Sabrina E de Matos Almeida, José A B Chies. Novel genetic associations and gene–gene interactions of chemokine receptor and chemokine genetic polymorphisms in HIV/AIDS. AIDS, 2017. https://pubmed.ncbi.nlm.nih.gov/28358741/
​
J M Valverde-Villegas, R M de Medeiros, S E M Almeida, J A B Chies, et al. Immunogenetic profiling of 23 SNPs of cytokine and chemokine receptor genes through a minisequencing technique: Design, development and validation. Int J Immunogenet 2017. https://pubmed.ncbi.nlm.nih.gov/28374494/
​
Valverde-Villegas JM. La era -ómica de la inmunología: La inmunogenética de enfermedades infecciosas, el VIH como modelo. RDGBM, 2017. https://igbmgenetica.com/wp-content/uploads/2017/07/Valverde-2017.pdf
​
​Jacqueline M Valverde-Villegas, Bruno Paiva Dos Santos, Rúbia Marília de Medeiros, Vanessa Suñé Mattevi, Rosmeri Kuhmmer Lazzaretti, Eduardo Sprinz, Regina Kuhmmer, José Artur Bogo Chies. Endosomal toll-like receptor gene polymorphisms and susceptibility to HIV and HCV co-infection - Differential influence in individuals with distinct ethnic background. Hum Immunol, 2017. https://pubmed.ncbi.nlm.nih.gov/28062211/
​
J M Valverde-Villegas, B P dos Santos, M B Machado, M Jobim, L F Jobim, C Flores, D C Damin, P Portela, J A B Chies. G2848A and T-1237C polymorphisms of the gene and susceptibility to inflammatory bowel disease in patients from southern Brazil. Tissue Antigens, 2014. https://pubmed.ncbi.nlm.nih.gov/24571477/
​
B P dos Santos, J V Valverde, P Rohr, O A Monticielo, J C T Brenol, R M Xavier, J A B Chies. TLR7/8/9 polymorphisms and their associations in systemic lupus erythematosus patients from Southern Brazil. Lupus, 2012.
https://pubmed.ncbi.nlm.nih.gov/22065095/
​
​
​
​
​
​
​
Jacqueline María Valverde-Villegas, Mar Naranjo-Gomez , Mélusine Durand, David Rutagwera, Anne-Sophie Bedin, Chipepo Kankasa, Ségolène Debiesse, Nicolas Nagot, Edouard Tuaillon, Philippe Van de Perre, Jean-Pierre Molès. The CD133+ stem/progenitor-like cell subset is increased in human milk and peripheral blood of HIV-positive women. Front Cell Infect Microbiol, 2020. https://pubmed.ncbi.nlm.nih.gov/33102251/
​​​
Jacqueline María Valverde-Villegas, Mélusine Durand, Anne-Sophie Bedin, David Rutagwera, Chipepo Kankasa, Edouard Tuaillon, Nicolas Nagot, Philippe Vande Perre, Jean-Pierre Molès. Large stem/progenitor-like cell subsets can also be identified in the CD45- and CD45+/high populations in early human milk. J Hum Lact, 2019. https://pubmed.ncbi.nlm.nih.gov/31815589/
​
Joel Henrique Ellwanger, Jacqueline María Valverde-Villegas, Valéria de Lima Kaminski, Rúbia Marília de Medeiros, Sabrina Esteves de Matos Almeida, Breno Riegel Santos, Marineide Gonçalves de Melo, Fernanda Schäfer Hackenhaar, José Artur Bogo Chies. Increased IL-8 levels in HIV-infected individuals who initiated ART with CD4+ T cells counts <350cell/mm3 – A potential hallmark of chronic inflammation. Microbes Infect, 2019. https://pubmed.ncbi.nlm.nih.gov/32534178/
​
Anne-Sophie Bedin, Jean-Pierre Molès, David Rutagwera, Nicolas Nagot, Chipepo Kankasa, Thorkild Tylleskär, Jaqueline M Valverde-Villegas, Mèlusine Durand, Philippe Van de Perre, Edouard Tuaillon. MAIT cells, TCR γδ+ cells and ILCs cells in human breast milk and blood from HIV infected and uninfected women. Pediatr Allergy Immunol. 2019. https://pubmed.ncbi.nlm.nih.gov/30758074/
​
Jacqueline María Valverde-Villegas, Rúbia Marília de Medeiros, Joel Henrique Ellwanger, Breno Riegel Santos, Marineide Gonçalves de Melo, Sabrina Esteves de Matos Almeida, José Artur Bogo Chies. High CXCL10/IP-10 levels are a hallmark in the clinical evolution of the HIV infection. Infect Genet Evol. 2018. https://pubmed.ncbi.nlm.nih.gov/29122683/
​
Rúbia M de Medeiros, Jacqueline M Valverde-Villegas, Dennis M Junqueira, Tiago Gräf, Juliana D Lindenau, Marineide G de Mello, Priscila Vianna, Sabrina E M Almeida, Jose Artur B Chies. Rapid and Slow Progressors Show Increased IL-6 and IL-10 Levels in the Pre-AIDS Stage of HIV Infection. Plos One, 2016.https://pubmed.ncbi.nlm.nih.gov/27214135/
​
Jacqueline María Valverde-Villegas, Maria Cristina Cotta Matte, Rúbia Marília de Medeiros, José Artur Bogo Chies. New Insights about Treg and Th17 Cells in HIV Infection and Disease Progression. J Immunol Res, 2015. https://pubmed.ncbi.nlm.nih.gov/26568963/
​
​​
​​
​​
​​
Rúbia Marília de Medeiros, Jacqueline María Valverde-Villegas, Joel Henrique Ellwanger. Editorial: Host-virus interaction at the omics and ecology levels. Front. Immunol. 2023. https://pubmed.ncbi.nlm.nih.gov/37207198/
Joel Henrique Ellwanger, Philip Martin Fearnside, Marina Ziliotto, Jacqueline María Valverde-Villegas, Ana Beatriz G DA Veiga, Gustavo F Vieira, Evelise Bach, Jáder C Cardoso, Nícolas Felipe D Müller, Gabriel Lopes, Lílian Caesar, Bruna Kulmann-Leal, Valéria L Kaminski, Etiele S Silveira, Fernando R Spilki, Matheus N Weber, Sabrina E DE Matos Almeida, Vanusa P DA Hora, José Artur B Chies. Synthesizing the connections between environmental disturbances and zoonotic spillover. An Acad Bras Cienc, 2022. https://pubmed.ncbi.nlm.nih.gov/36169531/
Joel Henrique Ellwanger, Ana Beatriz Gorini da Veiga, Valéria de Lima Kaminski, Jacqueline María Valverde-Villegas, Abner Willian Quintino de Freitas, José Artur Bogo Chies. Control and prevention of infectious diseases from a One Health perspective. Genet Mol Biol. 2021. https://pubmed.ncbi.nlm.nih.gov/33533395/
Joel Henrique Ellwanger, Bruna Kulmann-Leal, Valéria L Kaminski, Jacqueline María Valverde-Villegas, Ana Beatriz G DA Veiga, Fernando R Spilki, Philip M Fearnside, Lílian Caesar, Leandro Luiz Giatti, Gabriel L Wallau, Sabrina E M Almeida, Mauro R Borba, Vanusa P DA Hora, José Artur B Chies. Beyond diversity loss and climate change: Impacts of Amazon deforestation on infectious diseases and public health. An Acad Bras Cienc, 2019. https://pubmed.ncbi.nlm.nih.gov/32321030/